UCNot yet recruiting
Objective Disease Control and Treatment Strategies in Ulcerative Colitis
Observational · No treatment assigned · Sites not listed yet · First Affiliated Hospital, Sun Yat-Sen University
Official record & contacts on ClinicalTrials.gov ↗
In plain English
What this trial is testing
Condition(s) listed: Ulcerative Colitis (Disorder). This is an observational study: researchers collect information (for example questionnaires, samples, or scans) but the study does not assign a treatment.
Who can join
- Ages 16 and older
- Any sex
Some of the main requirements, copied from the record:
- Age 18 years or older.
- Established diagnosis of ulcerative colitis based on accepted clinical, endoscopic, histological, and/or imaging criteria documented in routine clinical care.
- Received clinical care at one of the participating centers during the prespecified study period.
- Availability of sufficient clinical information to establish the participant's ulcerative colitis diagnosis and longitudinal observation period.
- Eligible for inclusion under the ethics-approved retrospective and/or prospective cohort procedures.
There are also 5 reasons someone might not be able to join (exclusion criteria). Only the trial team can confirm whether you qualify.
What's involved
- About 1000 participants are expected to take part.
- The study has 1 group.
- Start date: 2026-11-01 (planned).
- Main results expected around 2031-12-30 (estimate from the record).
- No study sites are listed yet. Check the official record for contact details.
Groups in this study
- Ulcerative Colitis Longitudinal Cohort
Main thing being measured
- Time Under Objective Uncontrolled Disease (Up to 36 months from the relevant index date)
In the researchers’ words
This multicenter longitudinal observational cohort study aims to characterize objective disease-control trajectories, treatment adaptation, and long-term clinical outcomes among adults with ulcerative colitis receiving routine clinical care. Longitudinal clinical information, laboratory biomarkers, endoscopic assessments, intestinal ultrasound when available, medication exposure, corticosteroid use, hospitalization,…
Words you might see
- Pruritus: itching; a common and often hard-to-treat symptom in cholestatic liver disease.
- Endoscopy: a camera exam inside the digestive tract.
- Biopsy / histology: a small tissue sample examined under a microscope.
General definitions, not specific to this trial.
This summary was written automatically from the official record using fixed templates (no AI), so it only says what the record says, and may leave things out.
Questions to ask your doctor and the trial team
- Am I likely to qualify, given my health history?
- What would I have to do, and how often would I need to visit?
- Could I get a placebo? What happens to my current treatment?
- What are the possible risks and benefits?
- Are travel or other costs covered?
- What happens after the trial ends?
Official details
| Status | Not yet recruiting |
|---|---|
| Phase | Observational |
| Study type | Observational |
| Conditions | Ulcerative Colitis (Disorder) |
| Lead sponsor | First Affiliated Hospital, Sun Yat-Sen University |
| Collaborators | Sixth Affiliated Hospital, Sun Yat-sen University |
| Enrollment | 1000 (estimated) |
| Start date | 2026-11-01 |
| Primary completion (est.) | 2031-12-30 |
| First posted | 2026-10-16 |
| Last updated | 2026-10-16 |
| Official title | A Multicenter Longitudinal Cohort Study of Objective Disease Control, Treatment Adaptation, and Long-Term Outcomes in Ulcerative Colitis |
| ClinicalTrials.gov ID | NCT07877636 |
Interventions
- Routine Clinical Care (Other)
No study-assigned intervention will be administered. Diagnostic assessments, medication selection, treatment optimization, treatment switching, hospitalization, surgery, and other clinical management decisions will be made by treating physicians according to routine clinical practice.
Full eligibility criteria (from the record)
Inclusion Criteria: * Age 18 years or older. Established diagnosis of ulcerative colitis based on accepted clinical, endoscopic, histological, and/or imaging criteria documented in routine clinical care. Received clinical care at one of the participating centers during the prespecified study period. Availability of sufficient clinical information to establish the participant's ulcerative colitis diagnosis and longitudinal observation period. Eligible for inclusion under the ethics-approved retrospective and/or prospective cohort procedures. Exclusion Criteria: * Diagnosis subsequently revised to Crohn's disease, isolated intestinal Behçet's disease, infectious colitis, ischemic colitis, or another non-ulcerative-colitis condition that better explains the participant's disease. Insufficient information to establish a reliable longitudinal observation period. Duplicate or irreconcilable patient identity records. Withdrawal of permission for use of prospectively collected research data where applicable. Any exclusion required by local ethics or regulatory requirements.
Locations (0)
No sites listed yet. The official record has contact information.
For contacts at each site, use the official record.
Information only, not medical advice. Talk to your doctor and the trial team before making any decision about a clinical trial.