Every PSC & IBD trial, in plain English

819 clinical trials that are recruiting now or about to start, for primary sclerosing cholangitis (PSC), Crohn’s disease and ulcerative colitis. Pulled from ClinicalTrials.gov and rewritten so you can actually read them.

PSC 41 Crohn’s 434Ulcerative colitis 395IBD (general) 146

Updated 2026-10-17 · Free · No sign-up · No tracking

What’s new this week

Trials first posted on ClinicalTrials.gov since 2026-10-10:

This is a Single-center, Prospective, Single-arm Clinical Study Designed to Evaluate the Efficacy and Safety of Oral Aeromonas sp. MTB Phage Therapy for Pouchitis in Patients With Ulcerative Colitis (UC). UC first posted 2026-10-16
Longitudinal Registry of Difficult-to-Treat Inflammatory Bowel Disease Crohn'sUC first posted 2026-10-16
Objective Disease Control and Treatment Strategies in Ulcerative Colitis UC first posted 2026-10-16
Risankizumab for Refractory Perianal Fistulizing Crohn's Disease Crohn's first posted 2026-10-13
Efficacy and Safety of TRA16 Administered Orally in Patients With Enteric Hyperoxaluria (EH). Crohn'sUC first posted 2026-10-13
Effect of Intestinal Carriage of *Pilosibacter Rotomagensis* on Intestinal Inflammatory Activity Crohn's first posted 2026-10-13

Since our last data check: 0 newly listed, 0 updated, 0 no longer recruiting.

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Newest PSC trials

PSCNot yet recruiting

Nemolizumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus

Phase 2 · Testing Nemolizumab-ilto · 1 site

Mayo Clinic · Updated 2026-09-28 · NCT07843420

PSCNot yet recruiting

The Safety and Efficacy of Upadacitinib in Refractory Autoimmune Related Cholangitis and Atopic Dermatitis With Moderate to Severe Itching

Phase 2 · Testing Upadacitinib 15 MG · 1 site

RenJi Hospital · Updated 2026-07-01 · NCT07678645

PSCUCNot yet recruiting

Vancomycin Efficacy in Response to Dysbiosis in Atypical Colitis

Phase 2 · Testing Oral Vancomycin · 1 site

Tampere University Hospital · Updated 2026-09-10 · NCT07646223

See all 41 PSC trials →

Newest trials overall

UCNot yet recruiting

This is a Single-center, Prospective, Single-arm Clinical Study Designed to Evaluate the Efficacy and Safety of Oral Aeromonas sp. MTB Phage Therapy for Pouchitis in Patients With Ulcerative Colitis (UC).

Early Phase 1 · Testing MTB-targeted phage therapy · 1 site

Jinling Hospital, China · Updated 2026-10-16 · NCT07878026

Crohn'sUCNot yet recruiting

Longitudinal Registry of Difficult-to-Treat Inflammatory Bowel Disease

Observational · No treatment assigned · Sites not listed yet

First Affiliated Hospital, Sun Yat-Sen University · Updated 2026-10-16 · NCT07877649

UCNot yet recruiting

Objective Disease Control and Treatment Strategies in Ulcerative Colitis

Observational · No treatment assigned · Sites not listed yet

First Affiliated Hospital, Sun Yat-Sen University · Updated 2026-10-16 · NCT07877636

Crohn'sNot yet recruiting

Risankizumab for Refractory Perianal Fistulizing Crohn's Disease

Phase 4 · Testing Risankizumab · 4 sites

Yuki Horio · Updated 2026-10-13 · NCT07872449

Crohn'sUCNot yet recruiting

Efficacy and Safety of TRA16 Administered Orally in Patients With Enteric Hyperoxaluria (EH).

Phase 2 · Testing TRA16 · Sites not listed yet

Wuhan Kangfude Urolithiasis Research Institute Co., Ltd. · Updated 2026-10-13 · NCT07871669

Crohn'sNot yet recruiting

Effect of Intestinal Carriage of Pilosibacter Rotomagensis on Intestinal Inflammatory Activity

Observational · No treatment assigned · 1 site

University Hospital, Rouen · Updated 2026-10-13 · NCT07871383

Browse and filter all 819 trials →

PSC drug pipeline

Norucholic acid (nor-UDCA) and volixibat are the two PSC drugs closest to a regulatory decision. See where every late-stage PSC drug stands, with sources.

See the PSC pipeline